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IVF (In-Vitro-Fertilization) is a technique where a woman’s eggs are removed from her ovaries and fertilised with the man’s prepared sperm sample in the laboratory. The woman is given medication to stimulate the ovary to produce several eggs. These are removed by trans-vaginal ultrasound guidance under anaesthesia requiring a few hours of hospitalization. The eggs and sperm are then allowed to fertilize overnight in a petri dish in the lab and develop in the incubators for 2-6 days. The best embryos are then put back into the uterus to achieve pregnancy. Additional good quality embryos, if available, are frozen for future use. In Charitos BO Hospital, we carry out comprehensive laboratory fertility investigations to decide the best procedure possible.
A woman’s age is the most important factor for having a successful pregnancy when using her own eggs. If you are under 35 and considering an IVF, the good news is that your success rates are relatively promising!
In Charitos BO Hospital, success rate is amazingly 60%.
The three hundred thousand naira only (N300,000.00) for IVF in the on going Low Coat IVF covers only the Technical Fees. This Low Cost IVF is only for a single IVF trial. For those that may want 2cycles or 3cycles, you are expected to speak with the fertility specialist directly on +234 8033 450 127
Low Cost IVF price does not include egg donor, sperm donor, sex selection (PGD), Surrogacy and any other fertility related surgeries.
For all IVF cases that may require egg donor, sperm donor, sex selection or preimplantation genetic diagnosis (PGD), Surrogacy, IVF 2Cycles, IVF 3Cycles and any other fertility related surgeries should be complicated with our fertility specialist Dr. Benprosper ONOJA directly on +234 803 3450 127 for prompt response.
IVF SUCCESS RATE
Success rates for IVF depend on a number of factors;
I. Where you’re having the procedure done
II. Your age.
In Charitos BO Hospital, IVF success rate is amazingly 60%
Infertility is a condition of the reproductive system that prevents conception of children and is defined as failure to conceive after 12 months or more of regular unprotected sexual intercourse. About 80 % of couples who are regularly trying for a baby get pregnant within a year. An estimated one in seven couples has difficulty conceiving and women are usually less fertile as they get older.
This is a terminology used to describe the different treatment options available to help those who have difficulty in conceiving a child naturally. These options usually involve handling and manipulation of eggs and / or sperm in the lab to carry out simple procedures like artificial insemination / intrauterine insemination (IUI) or more advanced procedures including in-vitro fertilisation (IVF), intra-cytoplasmic sperm injection (ICSI) and various other treatments.
Detailed assessment and management of couples with:
WHAT TO EXPECT | IVF STEP BY STEP
IVF involves several steps; ovarian stimulation, egg retrieval, sperm retrieval, fertilization and embryo transfer. One cycle of IVF can take about two to three weeks. More than one cycle may be needed.
Ovulation induction
The start of an IVF cycle begins by using synthetic hormones to stimulate the ovaries to produce multiple eggs rather than the single egg that typically develops each month. Multiple eggs are needed because some eggs won’t fertilize or develop normally after fertilization.
Several different medications may be used, such as:
Medications for ovarian stimulation.
To stimulate your ovaries, you might receive an injectable medication containing a follicle-stimulating hormone (FSH), a luteinizing hormone (LH) or a combination of both. These medications stimulate more than one egg to develop at a time.
Medications for oocyte maturation. When the follicles are ready for egg retrieval — generally after eight to 14 days — you will take human chorionic gonadotropin (HCG) or other medications to help the eggs mature.
Medications to prevent premature ovulation. These medications prevent your body from releasing the developing eggs too soon.
Medications to prepare the lining of your uterus. On the day of egg retrieval or at the time of embryo transfer, your doctor might recommend that you begin taking progesterone supplements to make the lining of your uterus more receptive to implantation.
Your doctor will work with you to determine which medications to use and when to use them.
Typically, you’ll need one to two weeks of ovarian stimulation before your eggs are ready for retrieval. To determine when the eggs are ready for collection, you may have:
Vaginal ultrasound, an imaging exam of your ovaries to monitor the development of follicles — fluid-filled ovarian sacs where eggs mature
Blood tests, to measure your response to ovarian stimulation medications — estrogen levels typically increase as follicles develop, and progesterone levels remain low until after ovulation
Sometimes IVF cycles need to be canceled before egg retrieval for one of these reasons:
Inadequate number of follicles developing
Premature ovulation
Too many follicles developing, creating a risk of ovarian hyperstimulation syndrome
Other medical issues
If your cycle is canceled, your doctor might recommend changing medications or their doses to promote a better response during future IVF cycles. Or you may be advised that you need an egg donor.
Egg retrieval
Egg retrieval can be done in your doctor’s office or a clinic 34 to 36 hours after the final injection and before ovulation.
During egg retrieval, you’ll be sedated and given pain medication.
Transvaginal ultrasound aspiration is the usual retrieval method. An ultrasound probe is inserted into your vagina to identify follicles. Then a thin needle is inserted into an ultrasound guide to go through the vagina and into the follicles to retrieve the eggs.
If your ovaries aren’t accessible through transvaginal ultrasound, an abdominal ultrasound may be used to guide the needle.
The eggs are removed from the follicles through a needle connected to a suction device. Multiple eggs can be removed in about 20 minutes.
After egg retrieval, you may experience cramping and feelings of fullness or pressure.
Mature eggs are placed in a nutritive liquid (culture medium) and incubated. Eggs that appear healthy and mature will be mixed with sperm to attempt to create embryos. However, not all eggs may be successfully fertilized.
Sperm retrieval
If you’re using your partner’s sperm, a semen sample needs to be provided at your doctor’s office or clinic the morning of egg retrieval. Typically, the semen sample is collected through masturbation. Other methods, such as testicular aspiration — the use of a needle or surgical procedure to extract sperm directly from the testicle — are sometimes required. Donor sperm also can be used. Sperm are separated from the semen fluid in the lab.
Fertilization
Fertilization can be attempted using two common methods:
Conventional insemination. During conventional insemination, healthy sperm and mature eggs are mixed and incubated overnight.
Intracytoplasmic sperm injection (ICSI). In ICSI, a single healthy sperm is injected directly into each mature egg. ICSI is often used when semen quality or number is a problem or if fertilization attempts during prior IVF cycles failed.
In certain situations, your doctor may recommend other procedures before embryo transfer.
Assisted hatching. About five to six days after fertilization, an embryo “hatches” from its surrounding membrane (zona pellucida), allowing it to implant into the lining of the uterus. If you’re an older woman, or if you have had multiple failed IVF attempts, your doctor might recommend assisted hatching — a technique in which a hole is made in the zona pellucida just before transfer to help the embryo hatch and implant. Assisted hatching is also useful for eggs or embryos that have been previously frozen as the process can harden the zona pellucida.
Preimplantation genetic testing. Embryos are allowed to develop in the incubator until they reach a stage where a small sample can be removed and tested for specific genetic diseases or the correct number of chromosomes, typically after five to six days of development. Embryos that don’t contain affected genes or chromosomes can be transferred to your uterus. While preimplantation genetic testing can reduce the likelihood that a parent will pass on a genetic problem, it can’t eliminate the risk. Prenatal testing may still be recommended.
Embryo transfer
Egg retrieval
Egg-retrieval techniqueOpen pop-up dialog boxICSI
ICSIOpen pop-up dialog boxA blastocyst
BlastocystOpen pop-up dialog box
Embryo transfer is done at your doctor’s office or a clinic and usually takes place two to five days after egg retrieval.
You might be given a mild sedative. The procedure is usually painless, although you might experience mild cramping.
The doctor will insert a long, thin, flexible tube called a catheter into your vagina, through your cervix and into your uterus.
A syringe containing one or more embryos suspended in a small amount of fluid is attached to the end of the catheter.
Using the syringe, the doctor places the embryo or embryos into your uterus.
If successful, an embryo will implant in the lining of your uterus about six to 10 days after egg retrieval.
After the procedure
After the embryo transfer, you can resume your usual daily activities. However, your ovaries may still be enlarged. Consider avoiding vigorous activity, which could cause discomfort.
Diagnostic Services For The Female Diagnostic Services For The Male Ovulation Induction And Follicle Tracking Intrauterine Insemination (IUI) In-Vitro Fertilisation Intracytoplasmic Sperm Injection (ICSI) Blastocyst TransferEmbryo Freezing And Frozen Embryo Transfer Micro-Surgical Sperm Aspiration Other Treatment
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